In 1950 The World Motorcycle Champion in the 500cc Class was dominated by Umberto Masetti from Italy riding the Gilera motorcycle.
The events was held over 6 legs as follows:
TOURIST TROPHY
Isle of Man (Mountain) June 9, 1950
Top Six Finishers
- G. Duke (GB) Norton
- A. Bell (IRL) Norton
- J. Lockett (GB) Norton
- L. Graham (GB) AJS
- H. Daniell (GB) Norton
- R. Armstrong (IRL) Velocette
Spa-Francorhamps / July 2, 1950
Top Six Finishers
- U. Masetti (ITA) Gilera
- N. Pagani (ITA) Gilera
- E. Frend (GB) AJS
- C. Bandirola (ITA) Gilera
- A. Artesiani (ITA) MV Agusta
- H. Hinton (AUS) Norton
Assen / July 8, 1950
Top Six Finishers
- U. Masetti (ITA) Gilera
- N. Pagani (ITA) Gilera
- H. Hinton (AUS) Norton
- C. Bandirola (ITA) Gilera
- E. McPherson (AUS) Norton
- S. Jensen (NZ) Triumph
Geneva / July 23, 1950
Top Six Finishers
- L. Graham (GB) AJS
- U. Masetti (ITA) Gilera
- C. Bandirola (ITA) Gilera
- G. Duke (GB) Norton
- H. Daniell (GB) Norton
- J. Lockett (GB) Norton
Belfats / Clady / August 18, 1950
Top Six Finishers
- G. Duke (GB) Norton
- L. Graham (GB) AJS
- J. Lockett (GB) Norton
- D. Dale (GB) Norton
- J. West (GB) AJS
- U. Masetti (ITA) Gilera
Monza / September 10, 1950
Top Six Finishers
- G. Duke (GB) Norton
- U. Masetti (ITA) Gilera
- A. Artesiani (ITA) MV Agusta
- A. Milani (ITA) Gilera
- C. Bandirola (ITA) Gilera
- D. Dale (GB) Norton
- U. Masetti (ITA) Gilera
- G. Duke (GB) Norton
- L. Graham (GB) AJS
- N. Pagani (ITA) Gilera
- C. Bandirola (ITA) Gilera
- J. Lockett (GB) Norton
- A. Bell (IRL) Norton
- A. Artesiani (ITA) MV Agusta
- H. Hinton (AUS) Norton
- E. Frend (GB) AJS
- Norton - 28
- Gilera - 28
- AJS - 21
- MV Agusta - 6
- Triumph - 1
- Velocete - 1